Find dosing and administration information for BYDUREON Pen, including BYDUREON Pen packaging contains 4 pens .. BYDUREON [package insert]. Learn about BYDUREON® BCiseTM including efficacy, safety, PK profile, and dosing, and available resources, including Important Safety Information. Package Leaflet: Information for the user. Bydureon 2 mg powder and solvent for prolonged-release suspension for injection in pre-filled pen exenatide. Read all.
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Glucose monitoring is important when initializing or adjusting mecasermin therapies, when adjusting concomitant antidiabetic therapy, and in the event of hypoglycemic symptoms.
Possible mechanisms include atypical antipsychotic-induced insulin resistance or direct beta-cell inhibition. Exenatide may be used with basal insulin regimens. Its use is commonly associated with gastrointestinal adverse effects, including nausea, vomiting, and diarrhea.
Patients treated with lanreotide may experience either hypoglycemia or hyperglycemia. In patients with type 2 diabetes, exenatide moderates glucagon secretion and lowers serum glucagon concentrations during periods of hyperglycemia. As part of the glucose tolerance factor molecule, chromium appears to facilitate the byduteon of insulin to insulin receptors in tissues and to aid in glucose metabolism.
It appears that the effects of thiazide ibsert on glycemic control are dose-related and low doses can be instituted without deleterious effects on glycemic control. Exenatide has been studied in patients 65 years of age or older during clinical trials; safety and efficacy were not different in older adult patients versus younger adult patients.
When carrying the pen away from home, store the pen at a temperature between 36 to 77 degrees F 2 to 25 degrees C and keep dry. Recommendations will be communicated once the review is complete; continue to consider precautions related to pancreatic risk until more data are available. Minor The hydantoin anticonvulsants ethotoin, fosphenytoin and phenytoin can decrease the hypoglycemic effects of incretin mimetics by producing an increase in blood glucose levels.
Discontinue the quinolone if a hypoglycemic reaction occurs bdureon initiate appropriate therapy immediately. Also, while the manufacturers of metformin recommend against breast-feeding while taking the drug, metformin may be a possible alternative for some patients. In most individuals, concentrations of the regular-release injection solution Byetta are measurable for approximately 10 hours post-dose.
Hyperglycemia has developed in patients with diabetes mellitus following discontinuation of the drug. Patients on antidiabetics should be monitored for changes in blood glucose control if triamterene is added or deleted.
Bydureon (exenatide) dose, indications, adverse effects, interactions from
Acetaminophen; Butalbital; Caffeine; Codeine: Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine: Exenatide restores first-phase insulin response to an IV bolus of glucose.
If a breast-feeding infant experiences an adverse effect related to a maternally ingested drug, healthcare providers are encouraged to report the adverse effect to the FDA. Conversely, patients should be closely monitored for signs pacjage hypoglycemia when therapy with a hydantoin is discontinued. Exenatide is contraindicated in any patient who has exhibited exenatide hypersensitivity or hypersensitivity to any of its inactive ingredients.
Exenatide also slows gastric emptying thereby reducing the rate at which meal-derived glucose appears in the circulation. Major Pacjage may be used with basal insulin such as insulin degludec. Moderate Pentamidine can be bydureom to pancreatic cells. The clinical effects of these competing mechanisms are not known. Pen needles for the Byetta Pen are not included and must be purchased separately.
It is acceptable for the injections to be in the same body region but the injections should NOT be adjacent to each other. Moderate Animal data indicate that monoamine oxidase inhibitors MAOIs may stimulate insulin secretion.
For treatment of cold symptoms, nasal decongestants may be preferable for short term, limited use 1 to 3 days as an alternative to systemic decongestants in patients taking medications for diabetes. Similar absorption is achieved with subcutaneous administration of exenatide in the abdomen, thigh, or arm. Ybdureon large doses, salicylates uncouple oxidative phosphorylation, deplete hepatic and muscle glycogen, and cause hyperglycemia and glycosuria.
Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine: Careful monitoring of blood glucose is recommended. Double-check dosage prior to administration. Hemodialysis Exenatide is not recommended for use in patients with end-stage renal disease ESRD on continuous or intermittent hemodialysis. Diabetes medication pens should never be shared among patients.
Although specific dose recommendations are not available, a lower dose of the insulin or secretagogue may be required to reduce the risk of hypoglycemia in this setting. Patients should be aware byrureon the need to have a readily available source of glucose dextrose, d-glucose or other carbohydrate to treat hypoglycemic episodes.
Initiation with 5 mcg reduces the incidence and severity of gastrointestinal side effects. Patients who develop severe abdominal pain while on exenatide should be evaluated pakcage this could be a warning sign for a serious condition. Diabetic patients should be monitored for pacoage hypoglycemic reactions while on linezolid. Finally, both thiazides and sulfonylureas have been reported to cause photosensitivity reactions; concomitant use may increase the risk of photosensitivity.
Replace the blue cap after injection. Close monitoring of blood glucose is necessary for individuals who use antidiabetic agents whenever there is a change in thyroid treatment. The day of weekly administration can be changed if needed, as long as the last dose was administered 3 or more days before.